The Jackson Laboratory

Center for Biometric Analysis

What We Do

At the Center for Biometric Analysis (CBA), we empower JAX scientists with cutting-edge in vivo mouse phenotyping services. Our expertise spans a wide range of biological domains and disease states. Beyond data acquisition, we offer comprehensive support through experimental design consultation, staff training, and rigorous data quality control, statistical analysis, and interpretation.

Services and Technologies Offered

The CBA offers comprehensive in vivo mouse phenotyping services through four specialized cores:

  • Neurobehavioral Phenotyping (NBP core)
  • Physiology and Cardiac Phenotyping (PCP core)
  • Metabolic Phenotyping (MEP core)
  • Pre-clinical Imaging (PCI core)

Each core provides a range of services tailored to specific research needs. As our equipment and technologies evolve, the services we offer may also change to ensure we continue to meet the highest standards of scientific research.

Assays by Service Core

NBP Circadian Activity Monitoring (Wheels)PCP Intraocular Pressure Measurement, Non-Invasive
NBP Elevated Zero MazePCP Optical Coherence Tomography
NBP Delayed Spatial Alternation (Y-Maze)PCP Piezoelectric Sleep Monitoring
NBP Fear Conditioning, Contextual and CuedPCP Slit Lamp Ophthalmoscopy
NBP Frailty ScreenPCP Visual Acuity
NBP Gait Analysis (Treadscan)PCP Visual Evoked Potential
NBP Grip StrengthMEP Body Composition Analysis-EchoMRI
NBP Grooming, Induced and SpontaneousMEP Body Weight
NBP Home Cage Monitoring (Phenotypers)MEP Indirect Calorimetry
NBP Home Cage Wheel Running (Wheels)MEP Insulin Tolerance Test
NBP Hot PlateMEP Glucose Tolerance Test-Intraperitoneal
NBP Light/Dark BoxMEP Glucose Tolerance Test-Oral
NBP Nest BuildingMEP Glucose Tolerance Test with Insulin-Oral
NBP Novel Object RecognitionMEP Hyperglycemic Clamps (Glucose Clamps)
NBP Open FieldMEP Mixed Meal Tolerance Test
NBP Passive AvoidanceMEP Mixed Meal Tolerance Test with C-peptide
NBP Place Object RecognitionMEP Treadmill Activity
NBP Pre-pulse Inhibition/Startle ReflexPCI MRI-Anatomical
NBP RotarodPCI MRI-Angiography
NBP Social Approach (3-Chamber)PCI MRI-Diffusion Tensor Imaging
NBP Spontaneous Alternation-Visual Cues (Y-Maze)PCI MRI-Diffusion Weighted Imaging, Isotropic
NBP Tail WithdrawalPCI MRI-Neurite Orientation Dispersion and Density Imaging
NBP Von FreyPCI MRI-Neuroanatomical
PCP Auditory Brainstem ResponsePCI MRI-Neuroanatomical, Isotropic
PCP Blood Pressure, Non-InvasivePCI MRI-Resting State Functional (rsfMRI)
PCP Direct & Indirect Ophthalmic ExamPCI MRI-rsfMRI, Isotropic (imaging acquisition only)
PCP Distortion Product Otoacoustic EmissionPCI MRI Susceptibility Weighted Imaging
PCP DSI Telemetry Cardiovascular Blood PressurePCI MRI-T2star Mapping, Isotropic
PCP DSI Telemetry EEG/EMG-Deep Brain EEGPCI uCT-in vivo Imaging
PCP DSI Telemetry EEG/EMG-SeizuresPCI uCT-ex vivo Imaging (Trabecular and Cortical Bone Quantification)
PCP DSI Telemetry EEG/EMG-SleepPCI 2D Digital X-ray Skeletal Imaging
PCP Electrocardiogram, AnesthetizedPCI Dual-Emission X-ray Absorptiometry
PCP ElectroretinographyPCI Ultrasonography
PCP Fundus Imaging/Fluorescence Angiography

 

PCP Gross Morphology Photography 

 

 

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